diff --git a/ansible/group_vars/all.yml b/ansible/group_vars/all.yml
index 45db661bbc..b4ef05a7a8 100644
--- a/ansible/group_vars/all.yml
+++ b/ansible/group_vars/all.yml
@@ -743,7 +743,6 @@ osprofiler_backend_connection_string: "{{ redis_connection_string if osprofiler_
 ####################
 # RabbitMQ options
 ####################
-rabbitmq_hipe_compile: "no"
 rabbitmq_user: "openstack"
 rabbitmq_monitoring_user: ""
 outward_rabbitmq_user: "openstack"
diff --git a/ansible/roles/rabbitmq/templates/rabbitmq.conf.j2 b/ansible/roles/rabbitmq/templates/rabbitmq.conf.j2
index 31983f4f7b..f897499dac 100644
--- a/ansible/roles/rabbitmq/templates/rabbitmq.conf.j2
+++ b/ansible/roles/rabbitmq/templates/rabbitmq.conf.j2
@@ -1,9 +1,6 @@
 # NOTE(yoctozepto): rabbitmq uses the raw format (e.g. fd::) of IPv6 address;
 # despite specifying port via colon, the url format (e.g. [fd::]) is not accepted
 listeners.tcp.1 = {{ api_interface_address }}:{{ role_rabbitmq_port }}
-{% if rabbitmq_hipe_compile|bool %}
-hipe_compile = true
-{% endif %}
 {# NOTE: to avoid split-brain #}
 cluster_partition_handling = pause_minority
 
diff --git a/releasenotes/notes/deprecate-rabbitmq-hipe-compile-e76ad1d597129236.yaml b/releasenotes/notes/deprecate-rabbitmq-hipe-compile-e76ad1d597129236.yaml
new file mode 100644
index 0000000000..d7b1804002
--- /dev/null
+++ b/releasenotes/notes/deprecate-rabbitmq-hipe-compile-e76ad1d597129236.yaml
@@ -0,0 +1,5 @@
+---
+upgrade:
+  - |
+    Erlang 22.x dropped support for HiPE so the ``rabbitmq_hipe_compile``
+    variable has been removed.