To authenticate against an Image Service endpoint, instantiate a glanceclient.v2.client.Client object: from os import environ as env import glanceclient.v2.client as glclient import keystoneclient.v2_0.client as ksclient keystone = ksclient.Client(auth_url=env['OS_AUTH_URL'], username=env['OS_USERNAME'], password=env['OS_PASSWORD'], tenant_name=env['OS_TENANT_NAME'], region_name=env['OS_REGION_NAME']) glance_endpoint = keystone.service_catalog.url_for(service_type='image') glance = glclient.Client(glance_endpoint, token=keystone.auth_token)